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Contrave is looking very promising for the people seeking an eating plan pill that works well. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the risk of a possible boost in blood pressure.

Using two separate drugs to shed weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it you ought to err to the side of caution and let the FDA do its job and demand some investigation be done in order that the public understands the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say almost anything to keep people on their own medications.

Researchers discovered that participants investing in this drug for any year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which might be made up of multiple active ingredient, that might make them more potent and safer.

Combo-pilling is the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular may be the fact that by right now there are not any long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA.

Seizures are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug may also raise hypertension and heart rate, and really should not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.


From a psychiatric perspective, evidence shows that the ordinary neural mechanism for goal-directed behavior has become hijacked with the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus along with the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).